Exposure to fine Particle (PM2.5) and its association with respiratory health of workers at a bus terminal in Kuala Lumpur

Ghazali, Nur Izzati (2013) Exposure to fine Particle (PM2.5) and its association with respiratory health of workers at a bus terminal in Kuala Lumpur. [Project Paper] (Submitted)

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Abstract

Introduction: Exposures to PM2.5 have been shown to affect the respiratory health of the workers. Objectives: The aim of this study was to determine the association between particulate matters 2.5 (PM2.5) and its association with respiratory health. Methods: 50 study participants at the bus terminal were selected randomly. Exposure level of PM2.5was measured at three different places in bus terminal. All respondents were participated in lung function test and the analysis of urine IL-6 concentration. Questionnaire adapted from International Union against Tuberculosis and Lung Disease (IDA TLD) Bronchial Symptoms Questionnaires were distributed to the selected potential study participants. Result: The result shown that exposure level of PM2.5 at ticketing counter and boarding area were higher compared to the office. The average PM2.5 level for eight hours of monitoring at the management office, ticketing counter and boarding area were 5.44, 31.61 and 32.19 g/m3 respectively (World Health Organization PM2.5 level of 25g/m3). Prevalence of cough was higher among the non-office study participants (32%) compared to office study participants (16%). Mann-Whitney U test results showed that the mean exposure levels of IL-6 for office study participants were 0.25±0.13 pg/ml and non-¬office study participants were 0.2l±0.09 pg/ml. There is no significant difference between IL-6 among office and non -office study participants, z=-1.56, p=0.12. Negative correlations were found between the exposure levels of PM2.5and concentration of IL-6. Spearman correlation test was used to see the correlation between lung function and concentration of IL-6. From the analysis result, the FEVI % predicted and FVC % predicted showed no significant association r=0.18; p=0.21 and r=-O.IO; p=0.51 respectively. However, for ratio FEVl/FVC showed significant association with concentration of IL-6, r=0.31 p=0.03. Results also showed that there was negative correlation between lung function and concentration of PM25. However, the study participants who were exposed to higher level of PM2.5 were more likely to report respiratory illnesses compared to those exposed to lower levels of PM2.5. Conclusion: Although the level of IL-6 and PM2.5Were only slightly higher than the given standards, more attention should be given on the control of high level of exposure to PM2.5 in order to minimize the adverse health effects among the study participants in bus terminal. Keywords: PM25, IL-6, lung function, respiratory symptoms, bus terminal

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Mr Muhamad Fazril Awang
Date Deposited:	19 Sep 2022 03:58
Last Modified:	22 Aug 2023 04:23
URI:	http://psaspb.upm.edu.my/id/eprint/102

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