Transmission electron microscopic structure of the guttural pouch

Ariffin, Ema Arzairima (2017) Transmission electron microscopic structure of the guttural pouch. [Project Paper] (Submitted)

Text lp FPV 2017 52.pdf Download (3MB)

Abstract

This study on the transmission electron microscopic structure of the guttural pouch (GP) in the horse is complementary to another study on the light and scanning electron microscopic (SEM) structure of the GP concurrently being undertaken. Both studies are aimed at identifying the possible passageway utilised by a fungal infection from the GP into the internal carotid artery (ICA). Referred to as guttural pouch mycosis (GPM), the fungal infection erode the wall of the said artery resulting in fatal haemorrhage. Under the transmission electron microscope (TEM), the epithelial cells of the GP showed two types of modification of their cell surfaces. The first type is the presence of cilia and microvilli on the surface of the tall columnar cell and mucus secretory cells respectively. The second type is the presence of tight junction between contiguous epithelial cells. However more interestingly is the enlarged intercellular space between contiguous epithelial cells, these spaces could be the passage through which mucus droplets from the underlying connective tissue transverse through the epithelium to be deposited on the surface of the mucosa of the GP. Observation on the passage of the mucus through the epithelial lining was demonstrated by SEM in the concurrent study. The present study which demonstrated the existence of distended intercellular spaces between contiguous epithelial cells lend support the passage of mucus droplets from the underlying connective tissue to the mucosal as hypothesised in the concurrent study. Thus based on the passage of the mucous droplets across the epithelial lining of the GP it can be concluded that the possible passage of the mycotic infection is similar to that of the mucous droplets but in the opposite direction. With numerous single layered wall capillaries in the connective tissue below the epithelium gaining entry into the capillaries would be with relative ease and hence on into the ICA.

Item Type:	Project Paper
Faculty:	Faculty of Veterinary Medicine
Depositing User:	Ms. Nordeena Abdul Aziz
Date Deposited:	14 Apr 2023 01:29
Last Modified:	14 Apr 2023 01:29
URI:	http://psaspb.upm.edu.my/id/eprint/1067

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