Pesticide exposure, blood cholinesterase level and neurobeha vioral performance among paddy farmer at Tanjung Karang, Selangor

Othman, Muhammmad Izzat (2012) Pesticide exposure, blood cholinesterase level and neurobeha vioral performance among paddy farmer at Tanjung Karang, Selangor. [Project Paper] (Submitted)

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Abstract

Pesticides are widely used throughout the world especially in the agriculture and pest control as well as for community health purposed. Agriculture workers are exposed to pesticide primarily throughout mixing, spraying, and loading and clean up container placed the pesticides. The aim of this study was to determine whether pesticide exposure, blood cholinesterase level will affect the neurobehavioral performance score of the paddy field farmers. To fulfill this objective, total 94 of paddy farmers as exposed group and 30 farmers as control group completed a set of questionnaire, capillaries blood collected from finger prick technique for blood cholinesterase level by using cholinesterase test kit model LOVIBOND 412870 AF287 and Neurobehavioral Core Test Battery (NCTB) for neurobehavioral performance. From the result, it showed that mean of blood cholinesterase level for exposed group was lower than control group which was 34.841 and for control group was 88.333. The mean of total NCTB performance for exposed group was 350.24 while for control group was 388.27 and there were significant difference (p < 0.05) between both groups for entire NCTB test including the total NCTB performance. There were significant association (p < 0.05) between blood cholinesterase level with Digit Span Test, Digit Symbol Test, Reaction Time/Movement Test, Trail Making Test, Pursuit Aiming Test and the total NCTB performance. Duration of work (year) was the most significant variable that influence blood cholinesterase level (p .:S 0.001). Blood cholinesterase level was the most variable which influence the neurobehavioral performance, specifically for Benton Visual Retention Test (p = 0.037), Age and education level (year) were the most variables which influenced Reaction Time/Movement Test. In conclusion, duration of work (year) which indicated the exposure to pesticide decreased the blood cholinesterase level. The decreasing of blood cholinesterase level inversely Benton Visual Retention Test (visual memory function) and associated with neurobehavioral performance such as auditory memory, memory/manual dexterity coordination, response speed, motor steadiness and visual/steadiness coordination. Age and education level (year) were the variables which significantly influence Reaction Time/Movement Test (response speed function). Keyword: Pesticide, Neurobehavioral test, Cholinesterase enzyme IV

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Ms Norafizah Radzuan
Date Deposited:	21 Nov 2022 07:50
Last Modified:	25 Aug 2023 01:21
URI:	http://psaspb.upm.edu.my/id/eprint/137

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