Zainuddin, Nur Izuin (2020) Evaluation of the mucosal immune response of red hybrid tilapia to different doses of spray Streptococcus agalactiae vaccine. [Project Paper] (Submitted)
![[img]](http://psaspb.upm.edu.my/style/images/fileicons/text.png) |
Text
lp FPV 2020 16.pdf Download (2MB) |
Abstract
Streptococcus agalactiae is one of the important pathogens that can cause substantial mortality and morbidity among various species of freshwater, estuarine and marine fishes. This study was aimed to evaluate the mucosal immune response in red hybrid tilapia following administration of a single- and triple-dose of spray killed vaccine of S. agalactiae. 90 tilapia were randomly separated into 3 groups; Group 1, Group 2, and Group Cx. Group 1 were sprayed with formalin-killed bacteria (FKB) of S. agalactiae once per day. For Group 2, the fish were vaccinated once per day for 3 consecutive days. Group 3 served as the control group without any vaccination. Both Group 1 and Group 2 were given a booster 2 weeks after the first vaccination. All groups were then challenged with pathogenic S. agalactiae through intraperitoneal (i.p.) injection. Any clinical signs and mortality were recorded following the vaccination challenge trial. 3 fish from each group were sacrificed each week and skin samples were collected for histology. The changes in skin epidermal thickness every week was recorded. Statistical analysis of the epidermal skin thickness revealed that there is no significant difference in immune response produced by tilapia that is exposed to single-dose and triple dose spray-killed vaccine in tilapia. This showed that a single dose spray vaccination is sufficient to produce an immune response in Red hybrid tilapia.
| Item Type: | Project Paper |
|---|---|
| Faculty: | Faculty of Veterinary Medicine |
| Depositing User: | Ms Nurhaznita Mahmood |
| Date Deposited: | 19 Oct 2023 06:24 |
| Last Modified: | 19 Oct 2023 06:24 |
| URI: | http://psaspb.upm.edu.my/id/eprint/1478 |
Actions (login required)
 |
View Item |