Lee, Chye Tung (2021) Systematic review on streptococcus suis zoonotic potential. [Project Paper] (Unpublished)
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Abstract
Streptococcus suis (S suis) is a facultatively anaerobic Gram-positive bacteria, which lives as a normal flora in the upper respiratory tract, gastrointestinal tract, and genital tract of pigs. Clinical manifestations in swine include meningitis, septicaemia with sudden death, arthritis, and pneumonia. Interestingly, S suis can infect humans and lead to clinical signs similar to pigs. The objective of this systematic review is to review and identify the zoonotic potential and the predispose risks of S suis infection in humans. Articles were identified from three databases, namely Scopus, PubMed, and Science Direct. No time restriction was set in the searching, articles were included if they were written in English. Articles were excluded if they were duplicates or out of scope. Among 264 articles identified, 38 articles were included for this systematic review. A total of 718 cases were identified from 24 countries between 1968 and 2021. The mean age was 51 years old and 561 (78.13%) patients were male. Predispose risks identified include exposure to pigs or pork, pig-related occupations, skin injuries, underlying health conditions, and alcoholism. The case-fatality rate was 11.42%. Prevention of human S. suis infection can be done by public awareness and education. In this systematic review, we concluded that S. suis has zoonotic potential towards humans and the most frequent predispose risks was pigs or pork exposure. Nevertheless, further researches are needed to find out other possible source of infection or predispose risks, as well as for development of vaccine for humans.
| Item Type: | Project Paper |
|---|---|
| Faculty: | Faculty of Veterinary Medicine |
| Depositing User: | Ms Nurhaznita Mahmood |
| Date Deposited: | 04 Dec 2023 07:13 |
| Last Modified: | 04 Dec 2023 07:13 |
| URI: | http://psaspb.upm.edu.my/id/eprint/1546 |
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