Retrospective study on preoperative leukocytosis and its relationship with postoperative wound complications in cats and dogs presented for mastectomy at University Veterinary Hospital, Universiti Putra Malaysia from 2017 to 2021

Subramaniam, Sarweshwary (2022) Retrospective study on preoperative leukocytosis and its relationship with postoperative wound complications in cats and dogs presented for mastectomy at University Veterinary Hospital, Universiti Putra Malaysia from 2017 to 2021. [Project Paper] (Submitted)

Text lp FPV 2022 55.pdf Download (1MB)

Abstract

Human studies have suggested an association between preoperative leukocytosis and postoperative complications in various surgical procedures. Leukocytosis is often an incidental finding during pre-surgical blood screening. The association of leukocytosis with postoperative morbidity is inadequately addressed in the veterinary field. Leukocytosis is characterized by the elevation in white blood cell count above the upper range value of 19.5 x 109/L in cats and 14.1 x 109 /L in dogs. Mammary gland tumor is one of the most common tumors in small animals, in which mastectomy is the primary treatment indicated. The incidence of mammary gland tumors is 52% in dogs and 17% in cats of all tumors in females. Approximately 45% and 90% of mammary gland tumors are malignant in dogs and cats. Small animals undergoing mastectomy often develop surgical site wound complications such as seroma formation, wound infection, wound dehiscence, hemorrhage and inflammation. This study aims to identify the association between preoperative leukocytosis and postoperative wound complications in small animals undergoing mastectomy. This retrospective study included 62 patients: 36 were dogs and 26 were cats that underwent mastectomy for mammary gland tumors between the year 2017 to 2021 at University Veterinary Hospital, Universiti Putra Malaysia. Outcomes measured included wound complications such as inflammation, seroma formation, hemorrhage and suture breakdown during hospitalization. The frequency of preoperative leukocytosis in cats and dogs subjected to mastectomy was 62% and 47%, respectively. This study found an association between preoperative leukocytosis and postoperative wound complications (p ≤ 0.05). Patients with preoperative leukocytosis are more likely to develop postoperative wound complications than those without preoperative leukocytosis. Further studies are indicated to validate and explain these findings

Item Type:	Project Paper
Faculty:	Faculty of Veterinary Medicine
Depositing User:	Ms Nurhaznita Mahmood
Date Deposited:	29 Feb 2024 08:16
Last Modified:	29 Feb 2024 08:16
URI:	http://psaspb.upm.edu.my/id/eprint/1657

Actions (login required)

View Item