Blood cholinesterase level and cognitive functioning among primary school children near paddy field in Tanjung Karang, Selangor

Hamzah, Noor Aishah (2014) Blood cholinesterase level and cognitive functioning among primary school children near paddy field in Tanjung Karang, Selangor. [Project Paper] (Submitted)

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Abstract

Summary: Introduction: Based on Paddy Statistics of Malaysia 201 1, paddy is the third most widely planted crop in Malaysia after oil palm and rubber. In the year 201 1, 687,940 hectares were planted with paddy including those that are planted twice a year. The uses of pesticides lead to increase in yields and reduce product prices by partly protecting the plantation from any pest and unwanted plants. The extensive use of insecticide, may affect the human health especially from occupational and environmental exposures. Children are a vulnerable group to exposures of insecticides because of less-developed metabolism and the on-going maturation of their organ systems. Blood cholinesterase activity is the most effective biomarkers to measure the level of exposure for various pesticides. Objectives: The purpose of this study is to determine the relationship between blood cholinesterase levels with cognitive functioning of selected primary school children. Methodology: 112 primary school children were selected as an exposed group to the pesticides. The inclusive criteria were the children who study and lived near the paddy field. Their parents completed the questionnaire and 0.01 mL blood sample of the study respondents were collected from finger prick technique. The blood then was analyzed using Lovibond 412670 AF267 test kit to determine level of blood cholinesterase level. McCarthy Scale of Children's Ability (MSCA) was used to measure the cognitive functioning. Result: Highest percentage of respondents had normal (52.7%) exposure. About 92.9% reported with watery eyes of signs and normal (52.7%) exposure. About 92.9% reported with watery eyes of signs and symptoms from pesticide exposure. Most of the respondents were in average level (44.6%) of learning abilities. Conclusion: There was a significant relationship between blood cholinesterase levels with cognitive functioning in all scales of study group. No school children reported with borderline and mentally retarded cognitive functioning. Finally, gender, mother's education and blood cholinesterase showed signiticant intluenced in memory and motor scales in MSCA. Keywords: Pesticides, Human health, Environmental exposure, Biomarkers. Finger prick

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Ms Norafizah Radzuan
Date Deposited:	23 Nov 2022 03:45
Last Modified:	15 Feb 2023 01:12
URI:	http://psaspb.upm.edu.my/id/eprint/446

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