Occurrence of Fipronil, Imidacloprid and Pretilachlor in blood serum samples among paddy farmers in Tanjung Karang, Selangor

MUHAMMAD ANWAR, NURSARAH (2020) Occurrence of Fipronil, Imidacloprid and Pretilachlor in blood serum samples among paddy farmers in Tanjung Karang, Selangor. [Project Paper] (Submitted)

Text FPSK4 2020 7.pdf Download (1MB)

Abstract

Introduction: Nowadays, the demand of rice has increased. To sustain the continual supply of rice, farmers has been using pesticides due to its effectiveness of generating higher yields and product quality. However, the occupational exposure to the farmers are a concern as it can result in acute or chronic health effects. Objectives: The aim of this study was to quantify the concentration of the commonly used pesticide (fipronil, imidacloprid and pretilachlor) in blood serum sample and associate the concentration of the pesticide with the reported respiratory health symptoms among paddy farmers. Methodology: A cross-sectional study was carried out in Tanjung Karang, Selangor. Twenty-nine questionnaires were given to the farmers to obtain the self-reported respiratory health symptoms while blood serum samples were taken to analyze the concentration of pesticides. The sample was extracted using QuEChERS method (quick, easy, cheap, effective, rugged, and safe) then analyzed using the Ultra High Performance Liquid chromatography-mass spectrometry (UHPLC-MS/MS). Logistic regression was also used to identify the association of the compounds with the self-reported respiratory health symptoms. Results and Discussion: The study shows that the concentrations of the commonly used pesticide (fipronil, imidacloprid and pretilachlor) were 309.63 ngmL-1, 46.34 ngmL-1 and 195.97 ngmL-1, respectively. As for the reported health symptom, there was no significant association with the concentration of pesticides. There were other contributing factors such as work duration in years, weeks and hours, smoking and education that influenced the selfreported respiratory health symptoms. Conclusion: The preliminary findings of this study suggest that occupational exposure of pesticides may lead to occurrence of pesticides in blood serum samples of farmers. Since the pesticides are present in blood serum samples of farmers in a significant amount, further in depth studies are needed to study the health effects of the pesticides besides the self-reported respiratory health symptoms. Keywords: pesticides, blood serum sample, ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS/MS), QuEChERS method (quick, easy, cheap, effective rugged, and safe)

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Mr Hafizzuddin Hamidon
Date Deposited:	21 Feb 2023 01:17
Last Modified:	21 Feb 2023 01:17
URI:	http://psaspb.upm.edu.my/id/eprint/780

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