Asri, Amirul Amin and Palanisamy, Brentha and Mohd Rafiq, Nur Raziana (2021) Antimicrobial Utilisation at a newly opened tertiary hospital in Klang Valley (Hospital Pengajar UPM) in July 2020 and January 2021. [Project Paper] (Submitted)
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Abstract
Background: Antimicrobial agents are some of the most widely, and often injudiciously, used therapeutic drugs worldwide. Surveillance of antibiotic consumption in healthcare facilities is one of the important approaches in ensuring proper antimicrobial utilisation and controlling the emergence of antimicrobial resistance. The main objective of this study is to determine the antimicrobial utilisation at a newly opened tertiary hospital in Klang Valley (Hospital Pengajar Universiti Putra Malaysia, HPUPM) in July 2020 and January 2021. Methods: This study was conducted in Hospital Pengajar Universiti Putra Malaysia (HPUPM). The study design was retrospective and the duration of this study was 2 separate months (July 2020 and January 2021). The sample population was antimicrobial drug prescriptions of inpatients at HPUPM. The data regarding antimicrobial drugs prescribed for inpatients was included while data that did not meet the inclusion criteria was excluded. Data for this study was collected from the inpatient antimicrobial prescription records which was obtained from the Pharmacy Department of HPUPM. The data collected for this research was recorded in a proforma. The data collected was analyzed by using Statistical Package for Social Sciences (SPSS) version 26. Descriptive analysis was done for all variables in this study. The statistical tests used in this study were Kruskall-Wallis and Mann-Whitney tests. The test showed the association between the patient sociodemographic factors and amount of inpatient antimicrobial usage. Results: For the utilisation according to types and classes of antibiotics, the most frequently prescribed antibiotic in both months was Cefuroxime(42.24% in July 2020, 46.3% in January 2021). The antibiotic with the highest amount of usage was Pipreacillin in July 2020 (39.51%) whereas Cefuroxime in January 2021 (31.69%). The antibiotic class with the highest amount of usage was Penicillins in both months (57.78% in July 2020, 48.98% in January 2021). Beta lactam antibiotics had a higher amount of usage(99.22% in July 2020, 93.26% in January 2021) than non Beta lactam antibiotics in both months. For the sociodemographic factors, Male gender had higher usage in July 2020(58.7%) whereas Female gender had higher usage in January 2021(55.2%). The Malay ethnic had the highest antibiotic usage (65.2% in July 2020, 83% in January 2021) for both months. Medical ward had the highest antibiotic usage in July 2020(45.5%) whereas Neonatal Intensive Care Unit(NICU) had the highest usage in January 2 2021(34.6%). Ethnicity had a significant association with the antimicrobial usage amount of inpatients in July 2020 (p-value 0.002), but not in January 2021. Gender and Wards did not have a significant association with the inpatient antimicrobial usage in both months. Conclusion: In conclusion, July 2020 and January 2021 were similar in terms of the most frequently prescribed antibiotic type and most used class of antibiotics; but differed in terms of the most consumed antibiotic type. In sociodemographic factors, ethnicity in July 2020 was the only factor that had an association with antimicrobial usage. Further monitoring of antimicrobial utilisation needs to be enforced in this hospital since the most consumed antibiotics in both months(Cefuroxime and Piperacillin) were from the WHO “Watch” category which have higher resistance potential.
| Item Type: | Project Paper |
|---|---|
| Faculty: | Faculty of Medicine and Health Science |
| Depositing User: | Ms Norafizah Radzuan |
| Date Deposited: | 04 Sep 2023 04:33 |
| Last Modified: | 04 Sep 2023 04:33 |
| URI: | http://psaspb.upm.edu.my/id/eprint/1053 |
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