Mohamad Nasri, Nuruljannah (2020) Determination of carbohydrate composition in breast milk and its association with infant’s growth and behaviour. [Project Paper] (Submitted)
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Abstract
Breastfeeding is the gold standard of infant feeding, and it is very exclusive as its composition varies within a feed, diurnally and over lactation period. Carbohydrate is the major macronutrient found in breast milk, which comprises lactose and oligosaccharides, and has been suggested to be associated with infant health outcomes. Thus, this study aims to determine the breast milk carbohydrate composition and its association with infant’s growth and behaviour. A longitudinal observational study involving 64 infant-mothers dyads was conducted in Klang- Valley. Home visits were done at 2, 4-6 and 8-12 weeks of infant’s age. Infant’s weight and height were measured, and body weight status was determined. Infant’s appetite and behaviour were assessed using the Baby-Eating-Behaviour Questionnaire and 3-Day Infant Behaviour Diary, respectively. Breast milk was collected for fore- and hind-milk at all home visits. Total carbohydrate was determined using human milk analyzer, whereas lactose was determined using highperformance liquid chromatography. The mean weight-for-age and BMI-for-age at week 8-12 were -0.50±0.87 and -0.99±1.01, respectively, indicating a normal growth pattern. Breast milk contains an average of 7.08 ± 0.31g/dL and 7.15 ± 0.20g/dL for total carbohydrate and lactose, respectively, showing an expected level based on literature. Carbohydrate composition was stable across different time-points and within feeding (p>0.05). Total milk carbohydrate was positively correlated with infant weight at week 8-12 (r=0.314, p<0.05), but no significant association was found for lactose per say. No association was found between carbohydrate composition and infant outcomes e.g. appetite, feeding and sleeping behaviour. In conclusion, total carbohydrate was associated with infant weight at later time point of the study, but no association was found with other variables. As milk contains various nutrient and bioactive factors, future research with larger sample size shall explore the potential roles of milk composition for infant’s well-being.
| Item Type: | Project Paper |
|---|---|
| Faculty: | Faculty of Medicine and Health Science |
| Depositing User: | Ms Norafizah Radzuan |
| Date Deposited: | 04 Sep 2023 03:53 |
| Last Modified: | 04 Sep 2023 03:53 |
| URI: | http://psaspb.upm.edu.my/id/eprint/1259 |
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