Blood cholinesterase level and learning ability among primary school children in Tanjung Karang, Selangor

Miswon, Nurul Husna (2013) Blood cholinesterase level and learning ability among primary school children in Tanjung Karang, Selangor. [Project Paper] (Submitted)

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Abstract

Project paper (B.S.(Environmental & Occupational Health)) - Universiti Putra Malaysia, 2013. Introduction: Pesticides are widely used in agriculture for crop protection from any insects and plant growth improvement. The widespread use of organophosphate (OP) pesticide in paddy field has lead to exposure in human. These pesticides can be absorbed rapidly via respiratory, gastrointestinal, ocular and dermal system. The effects are particularly profound in children because at this phase they are active, their organ and system especially their cognitive functions are developing. Objective: The aim of the study was to determine the relationship between blood cholinesterase levels with learning ability of study group. Methodology: About 77 of primary school children who live near paddy field was selected as exposed group and 62 of primary school children located further away from agriculture site served as the unexposed group. Their parents completed the questionnaire. The children's capillaries blood was collected from finger prick technique to determine the levels of blood cholinesterase using cholinesterase test kit LOVIBOND 412870 AF287. The McCarthy Scales of Children's Abilities (MSCA) was used to determine the learning ability of these children. Result: There were significant differences (p<0.05) in blood cholinesterase and all scales in MSCA between the exposed and the unexposed group. There were significant associations between blood cholinesterase levels and learning ability by all scales in MSCA (p<0.05). Other variable that significantly influenced the blood cholinesterase was gender (p=0.008). Blood cholinesterase was the most significant influencing factor on the learning ability especially on the motor scale (p=0.002) . Conclusion: Blood cholinesterase levels had significant relationship with the learning ability of the study group especially the motor performance. Keyword: Pesticide, learning ability, enzyme cholinesterase

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Ms Nabilah Rozali
Date Deposited:	22 Nov 2022 00:58
Last Modified:	22 Nov 2022 00:58
URI:	http://psaspb.upm.edu.my/id/eprint/154

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