Cadmium concentration in budu and health risk assessment among resident in Tumpat, Kelantan

Hassan, Nor Husna (2012) Cadmium concentration in budu and health risk assessment among resident in Tumpat, Kelantan. [Project Paper] (Submitted)

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Abstract

Summary: Introduction: Budu is fish product which obtained by salt fermentation of anchovies or mixture of anchovies with other small fishes. Objectives: A cross-sectional study was conducted to determine cadmium concentration in budu, estimate the health risk among respondents and to determine relationship between frequency intake of budu with cadmium poisoning and health risk encountered by respondents. Methods: A total of 160 respondents were selected from the study areas based on a few inclusive criteria. Three budu samples were purchased from local mini market. The extraction of budu was performed by dry ashing method and cadmium concentration in budu was analyzed using Inductively Coupled Plasma Mass Spectrometer (ICP-MS). Results: Cadmium was detected in all budu samples at range level of 0.0317 to 0.0467 mg/kg which these concentrations not exceed the permissible limit (Img/kg) by Malaysia Food Regulation 1985. Health risk assessment indicated by average daily dose (ADD), lifetime average daily dose (LADD), hazard quotient (HQ) and lifetime excess cancer risk (LCR). The ADD and LADD value not exceed cadmium oral reference dose (5.0 x 10-4 mg/kg/day) and Provisional Tolerable Weekly Intake (PTWI) (0.007 mg/kg/weekly or 0.001 mg/kg/day). All the respondents had HQ «1) and LCR (> lxl0•6) which this results showed acceptable risk encountered by the respondents. The result of this study did not show any significant relationship between frequency intakes of budu and prevalence of cadmium poisoning signs. However, significant relationship was found between frequency intake with HQ (r=0.681, p <0.0001) and LCR (r=0.626, p <0.0001). Conclusion: cadmium was detected in budu samples and its concentration was not exceed the limit permitted by Malaysia Food Regulation 1985 and ADD, LADD, HQ and LCR values also not exceed acceptable limit. Recommended the respondents to monitor their cadmium level by perform biological sample check-up for cadmium exposure. Key word: Cadmium Concentration, Budu, Health Risk Assessment, ADD, LADD, HQ, LCR

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Ms Norafizah Radzuan
Date Deposited:	22 Nov 2022 06:17
Last Modified:	16 Feb 2023 03:33
URI:	http://psaspb.upm.edu.my/id/eprint/168

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