Antimicrobial resistance profiles in enterobacteriaceae isolates from fecal samples of synanthropic bats in UPM Serdang campus and surrounding areas

Meor Mohammad Fared, Sajidah Khadijah (2022) Antimicrobial resistance profiles in enterobacteriaceae isolates from fecal samples of synanthropic bats in UPM Serdang campus and surrounding areas. [Project Paper] (Submitted)

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Abstract

The emergence and spread of AMR bacteria are increasing in notoriety across public health sectors globally. Despite being vilified as disease vectors, pests, or creatures of malice, bats continue to flourish and adapt in a wide range of habitats, often living in human-dominated landscapes. Inevitably, it is speculated that the level of anthropogenic presence may influence the AMR carriage rate in these species. No previous research has ventured into characterizing antibiotic-resistant patterns in bats in Malaysia, hence, this study is the first to report on such findings. Fresh guano (n = 51) were collected from insectivorous (Scotophilus kuhlii and Hypsugo macrotis) and frugivorous (Cynopterus brachyotis) bats in UPM Serdang Campus, Ayer Hitam Forest Reserve (AHFR), and Malaysia Agro Exposition Park Serdang (MAEPS), Selangor. E. coli was the predominant Enterobacteriaceae isolated (45%, 81/179). Antibiotic sensitivity testing (AST) was performed using Kirby Bauer’s disk diffusion technique. In general, S. kuhlii had the most pronounced resistant pattern as E. coli isolates depicted resistance to most antimicrobials, more notably ampicillin, cephalexin, and streptomycin. Furthermore, odds ratio analysis was used to illustrate the occurrence of MDR E. coli and interestingly, E. coli from guano of S. kuhlii in CIMB UPM were 11.7 times more likely to develop multi-drug resistance compared to E. coli from guano of C. brachyotis in MAEPS (p-value < 0.05). In conclusion, AMR is a complex issue that can be mitigated by adopting the One Health approach and fine-tuning conservation strategies to suit the local context in preserving the natural habitats of bats in human-encroached space.

Item Type:	Project Paper
Faculty:	Faculty of Veterinary Medicine
Depositing User:	Ms. Nordeena Abdul Aziz
Date Deposited:	30 Apr 2024 07:59
Last Modified:	30 Apr 2024 07:59
URI:	http://psaspb.upm.edu.my/id/eprint/1736

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