Distribution, risk factors and survival analysis of dog diagnosed with dilated cardiomyopathy

Low, Xuen Kang (2022) Distribution, risk factors and survival analysis of dog diagnosed with dilated cardiomyopathy. [Project Paper] (Submitted)

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Abstract

Dilated cardiomyopathy (DCM) is the most common type of cardiomyopathy in dogs. This study determined the distribution, risk factors and effect of treatment compliance on the survival of dogs diagnosed with DCM. Log books of canine patients at the University Veterinary Hospital, University Putra Malaysia, between 2013 and 2022, were retrospectively analyzed, and the total number of dogs presented was obtained. Records of 116 dogs diagnosed with DCM were manually reviewed. Information such as breed, age, sex, date of diagnosis and deceased were recorded from cases with a confirmed diagnosis based on echocardiography. For cases with incomplete information, owners were contacted via phone to ascertain the dogs’ current health status, cause of death if the dog had deceased, and compliance with the prescribed medications. The risk factors of interest were analyzed using univariable and multivariable logistic regression. Median survival time (MST) was obtained through Kaplan-Meier Estimate. In this study, the distribution of dogs diagnosed with DCM was 1.07% (n=116/10846). Male dogs (OR: 1.52, 95%CI: 1.00 - 2.32), large breed dogs (OR: 7.08, 95%CI: 4.17 - 12.03) and medium breed dogs (OR: 2.91, 95%CI: 1.79 -4.72) had higher risk for DCM. Throughout the study period, 65 out of 116 DCM dogs succumbed to heart-related death. DCM dogs with compliant owners had significantly longer MST (549 days, 95%CI: 392.90 – 705.10) than those that did not receive treatment (148 days, 95% CI: 35.26 -260.74). Information obtained may allow clinicians to suggest screening and motivate owners to support long-term treatment in affected dogs.

Item Type:	Project Paper
Faculty:	Faculty of Veterinary Medicine
Depositing User:	Ms Nurhaznita Mahmood
Date Deposited:	30 May 2024 07:50
Last Modified:	30 May 2024 07:50
URI:	http://psaspb.upm.edu.my/id/eprint/1846

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