The distribution and risk factors of bacteria isolated from feline urinary tract infections and the antimicrobial resistance profile from 2017 to 2022

H’ng, Wann Jye (2023) The distribution and risk factors of bacteria isolated from feline urinary tract infections and the antimicrobial resistance profile from 2017 to 2022. [Project Paper] (Submitted)

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Abstract

Urinary tract infection (UTI) is a common uropathy affecting the feline population and may be the leading reason for antimicrobial prescription in companion animals. Many studies emphasised that the emergence of antimicrobial-resistant bacteria was related to the imprudent use of antibiotics. Locally, there was a lack of data on antimicrobial resistance in companion animals. This retrospective study assessed the distribution of bacteriuria in cats, the risk factors, and the antimicrobial resistance profile. A total of 312 cats suspected of UTI between January 2017 to December 2022 were identified, and the medical records were retrieved. Signalments such as age, breed, gender, management, and clinical history were recorded. Data was descriptively analysed, and the Pearson’s chi-squared test was conducted to analyse risk factors with a significant level (p = 0.05). About 84.0% of suspected UTI cats had bacteriuria with signs of haematuria (46.4%), stranguria (42.8%), inappetence (26.3%), pollakiuria (25.8%) and anuria (22.2%). Only gender showed a significant difference (p< 0.05, 95% CI), and male cats were at 2.9 times more risk for having bacteriuria. A total of 227 bacterial isolates had been identified, and predominantly, Escherichia coli (15.4%), Enterococcus faecalis (14.1%), Klebsiella pneumoniae (13.2%), Pseudomonas aeruginosa (10.6%) and followed by Proteus mirabillis (10.1 %) were isolated. These bacteria isolates showed high resistance to common antibiotics, including fluoroquinolones, penicillin, cephalosporin, and trimethoprim-sulphonamides. Broad-spectrum antibiotics were generally used against feline UTIs, causing the increasing trend of antimicrobial resistance. With clinical signs, a rational antimicrobial therapy adhered to guidelines should be given based on the urine culture result and antimicrobial susceptibility profile.

Item Type:	Project Paper
Faculty:	Faculty of Veterinary Medicine
Depositing User:	Ms. Nordeena Abdul Aziz
Date Deposited:	15 Nov 2024 01:25
Last Modified:	15 Nov 2024 01:25
URI:	http://psaspb.upm.edu.my/id/eprint/2111

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