Tay, Justin Hong Chuan (2023) Molecular detection of feline parvovirus and its risk factors among pet cats displaying gastrointestintal clinical signs in Selangor, Malaysia. [Project Paper] (Submitted)
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Abstract
Feline parvovirus is a highly contagious, single-stranded DNA virus that causes feline panleukopenia, also known as feline infectious enteritis. Feline panleukopenia is a serious, potentially fatal disease that affects cats of all ages. This study was conducted with the intent to determine the molecular detection rate of feline parvovirus and assess the risk factors that contribute to its transmission among pet cats in Selangor, Malaysia. Since no previous recent studies were done regarding feline parvovirus in Malaysia, the result of this study serves as a baseline database for future research. A total of 45 faecal samples from pet cats exhibiting signs of diarrhoea and/or vomiting were collected from small animal clinics in all nine districts within Selangor. DNA was extracted from each faecal sample using a DNA extraction kit and then subjected to PCR and agarose gel electrophoresis. Processed gel was viewed under a GeneSnap viewer machine to determine the result. Descriptive analysis was used to determine the molecular prevalence of feline parvovirus. The significance of association between risk factors and feline parvovirus infection was determined using Fisher’s Exact Test. Overall, 28 (62.2%) among 45 samples tested positive for FPV, where the districts with the highest prevalence rate were Petaling (83%), Gombak (80%), Sepang (80%) and Hulu Langat (67%). Several risk factors that indicate significant association with feline parvovirus positivity, include age (P<0.0001), outdoor management (P=0.0017) and vaccination status. The two vaccination statuses with significant association were unvaccinated and incompletely vaccinated (P<0.0001). In conclusion, there was high molecular detection rate of feline parvovirus in Selangor. The high molecular detection rate warrants immediate preventive action through routine core vaccination practice to curb the spread of this virus. This virus is fatal as there is currently no treatment for feline panleukopenia but only supportive care.
| Item Type: | Project Paper |
|---|---|
| Faculty: | Faculty of Veterinary Medicine |
| Depositing User: | Ms. Nordeena Abdul Aziz |
| Date Deposited: | 18 Nov 2024 02:56 |
| Last Modified: | 18 Nov 2024 02:56 |
| URI: | http://psaspb.upm.edu.my/id/eprint/2140 |
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