The relationship between factors associated with blood pressure decrement in hypertensive patients on regular hemodialysis in Hospital Serdang

Ahmad Zaki, Muhammad Amin (2012) The relationship between factors associated with blood pressure decrement in hypertensive patients on regular hemodialysis in Hospital Serdang. [Project Paper] (Submitted)

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Abstract

INTRODUCTION: Hypertension is a persistent elevation of systolic blood pressure (BP) of 140 mmHg or greater and/or diastolic BP of90 mmHg or greater. Hypertension is common and difficult to manage in patients with end stage renal disease (ESRD) on regular haemodialysis (HD). Most patients with ESRD developed complications from hypertension such as cardiovascular disease (CVD) which is the major cause of death in ESRD patients. Many studies were done on HD patients; however, the relationships between factors associated with blood pressure are not well defined. OBJECTIVE: This study aims to determine factors associated with blood decrement after haemodialysis in hypertensive patients on regular haemodialysis. There were three factors identified as contributing to the BP decrement; IDWG, antihypertensive medications and duration of HD. METHODOLOGY: A cross-sectional study with purposive sampling method was done involving a total of 124 respondents on regular haemodialysis in Haemodialysis Unit (HDU) Hospital Serdang, who fulfilled the study's inclusions criteria. A standardized Proforma was modified for the purpose of this study. RESULTS: There were 64(51.6%) males and 60(48.4%) females with average age of 51.4±13.1 years old. Most of them were Malay (54.8%) and 52.4% of the respondents had secondary level of education. Majority of respondents (53.2%) gained IDWG < 2.2kg with mean IDWG of2.25±1.2 kg. There were 52.4% of respondents on with one type of antihypertensive medication and 38.7% of respondents undergone haemodialysis treatment from 1 to 3 years. The mean predialysis systolic and diastolic BP values were 160.34±19.53 mmHg and 80.78±15.26 mmHg, respectively; while mean postdialysis systolic and diastolic BP were 128.75±19.75 mmHg and 73.87±13.27mmHg, respectively. Paired t-test showed there was significant difference between BP pre and post dialysis which showed significant BP decrement after dialysis; however the factors contributing to it was not determined clearly. In this study, there were significant correlations between IDWG and antihypertensive medications with BP decrement after haemodialysis with r = 0.18, P ::;0.05 and r = 0.22, P ::;0.05 respectively. However, no significant relationship was seen between the duration of HD and BP decrement. CONCLUSION: There were significant relationships between IDWG and antihypertensive medications with BP decrement after haemodialysis; however there was no significant relationship with the duration of HD. Further study is warrented in order to determine other factors which might involved in blood pressure control among haemodialysis patients. Key words: Interdialytic weight gain (IDWG), haemodialysis (HD), blood pressure (BP)

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Ms. Adni Syuhaida Zon
Date Deposited:	22 Nov 2022 07:40
Last Modified:	22 Aug 2023 01:31
URI:	http://psaspb.upm.edu.my/id/eprint/246

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