Seroprevalence of Japanese Encephalitis Virus (JEV) in Long-tailed Macaque (Macaca fascicularis) in Peninsular Malaysia

Hashim, Norsuzana (2016) Seroprevalence of Japanese Encephalitis Virus (JEV) in Long-tailed Macaque (Macaca fascicularis) in Peninsular Malaysia. [Project Paper] (Submitted)

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Abstract

Japanese Encephalitis Virus (JEV) is among the most important viral encephalitis in Asia caused by an envelope single stranded positive sense RNA virus genus of Flaviviridae and from family Flavivirus. JEV is maintained in zoonotic cycle with mosquito as vector, principally Culex tritaeniorhychus. Pig and aquatic bird are the reservoir and amplifying host whereas human, horse, wild and domestic mammals are the dead end hosts. According to WHO, JEV is widely endemic in the Southeast Asia and Western Pacific regions including Malaysia. However, there is no studies have been carried out to determine the prevalence of JEV antibody in macaque in Malaysia. Thus, this study was conducted to determine the seroprevalence of JEV in macaque in Peninsular Malaysia. A total of 44 serum samples of long-tailed macaque (Macaca fascicularis) collected from Pahang, Kelantan and Perlis and from different ages, sex and habitats were analyzed using quantitative competitive ELISA test. The result revealed that 9 of 44 monkeys (20.45%) were seropositive for JEV with highest prevalence in Kelantan (33.33%) compared to others state. As a conclusion, this study revealed that long tailed macaque in Peninsular Malaysia have been exposed to JEV infection. Further study should determine the genotype of the virus circulating on the macaque population by molecular studies.

Item Type:	Project Paper
Faculty:	Faculty of Veterinary Medicine
Depositing User:	Ms Siti Mariam Giman
Date Deposited:	22 Nov 2022 02:23
Last Modified:	22 Nov 2022 02:23
URI:	http://psaspb.upm.edu.my/id/eprint/416

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