Assessment of mutagenic activity from river water due to industrial effluent: a review

PATINADAN, PATRICIA (2020) Assessment of mutagenic activity from river water due to industrial effluent: a review. [Project Paper] (Submitted)

Text FPSK4 2020 11.pdf Download (1MB)

Abstract

Introduction: River water pollution is a deterioration of the surface water quality due to the influence of many types of pollutants in water body. One of the causes of river water pollution is the discharge of industrial effluents into the water bodies. These industrial effluents contain many contaminants such as heavy metals, acids and alkalis, dyes, aromatic amines and many more. The main health effect of interest from exposure to these river water contaminated with industrial effluents are changes in DNA or mutation, thus leading to cancer formation in living organism. Objectives: thus this study aimed to review the mutagenic activity present in river water due to discharge of industrial effluents by identifying the source and contaminant responsible in inducing mutagenic activity in river waters. In addition, this study aimed to assess mutagenic activity as one of the parameters in river water quality monitoring programme. Methodology: This review was done by incorporating keywords such as river water pollution, industrial effluent, mutagenicity and toxicity testing to search for research articles in the subscribed database such as Science Direct. Results and Discussion: It was found that the factors inducing mutagenic activity in river water includes the discharge of azo compounds or azo dyes, heavy metals and mixture of pollutants from varying sources. The assays such as Ames Test or Allium cepa test ere used in certain countries in their routine river water quality programme as screening process to assess the mutagenicity and lead to the detection of agents which causes DNA damage in organisms. Conclusion: In conclusion, agents causing mutation from industrial effluent has been identified from different sources. It is recommended to include the mutagenicity testing in annual river water quality programme in Malaysia to detect pollutants present in river water which causes DNA damage. Keywords: River water pollution, Industrial effluent, Mutagenicity, Toxicity testing

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Mr Hafizzuddin Hamidon
Date Deposited:	21 Feb 2023 01:14
Last Modified:	21 Feb 2023 01:14
URI:	http://psaspb.upm.edu.my/id/eprint/791

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