Occurrence of Difenoconazole, Tebuconazole, Tricyclazole and Propiconazole in blood serum samples among paddy farmers in Tanjung Karang, Selangor

KAMARULLAH, SYAZANA NABILAH (2020) Occurrence of Difenoconazole, Tebuconazole, Tricyclazole and Propiconazole in blood serum samples among paddy farmers in Tanjung Karang, Selangor. [Project Paper] (Submitted)

Text FPSK4 2020 41.pdf Download (1MB)

Abstract

Introduction: The high demand of rice consumption in Malaysia had urge a large production of crop and in order to meet this demand, and this leads to increase use of pesticide. Pesticides plays important roles in maintaining a good condition of crops in terms of quantity and also quality. However, increase use of pesticide in agricultural field gives concern towards farmers if they failed to wear appropriate personal protective equipment when they handling the pesticides. Objectives: The aim of the study is to quantify the concentration of difenoconazole, tebuconazole, propiconazole and tricyclazole in blood serum samples and its associate the reported health symptoms among farmers. Methodology: A total of 86 questionnaires on demographic and occupational were distributed to the farmers and their blood were extracted using QuEChERS method (quick, easy, cheap, effective, rugged and safe). The extracted were analysed using Ultra High Performance Liquid Chromatography Mass Spectrometry (UHPLC-MS/MS). Results and Discussion: The mean concentrations of difeconazole, tebuconazole, tricyclazole and propiconazole in blood serum samples among paddy farmers were 1063.18 ng/mL, 779.55 ng/mL, 638.52 ng/mL and 617.26 ng/mL, respectively. There is no significant association between concentration of pesticides in blood serum samples with the reported health symptoms(breathing difficulties and chest pain). There were other contributing factors such as work duration, smoking status and education level. Conclusion: As a conclusion, there is a significant value of concentration of pesticide in blood serum sample of farmers. The usage of personal protective equipment (PPE) according to Malaysian standard code of recommended practice (MS479:2012) were recommended. Further study should be conducted which may benefit relevant authorities. This study has a lot of challenges and limitation such as short period of time due to pandemic and the breakdown of UHPLC-MS/MS during the study period. Keywords:Pesticide, Blood Serum, ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS/MS), QuEChERS (quick,easy, cheap, effective, rugged, and safe)

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Mr Hafizzuddin Hamidon
Date Deposited:	24 Aug 2023 04:56
Last Modified:	24 Aug 2023 04:56
URI:	http://psaspb.upm.edu.my/id/eprint/854

Actions (login required)

View Item