Occurrence of Azoxystrobin and Trifloxystrobin in blood serum samples among paddy farmers in Tanjung Karang, Selangor

IBRAHIM, MUHAMMAD NAJMI (2020) Occurrence of Azoxystrobin and Trifloxystrobin in blood serum samples among paddy farmers in Tanjung Karang, Selangor. [Project Paper] (Submitted)

Text FPSK4 2020 47.pdf Download (1MB)

Abstract

Introduction: To meet the rising demand of rice in Malaysia, a sustainable production of paddy is in necessary. To generate higher yields and higher quality crops, farmers have been using pesticides to prevent diseases and pests. However, this usage of pesticides raises concerns as occupational exposure to pesticides can result in acute or chronic health effects. Objectives: The aim of this cross-sectional study was to quantify the concentration of the commonly used pesticide (azoxystrobin and trifloxystrobin) in blood serum sample and associate the concentration of the pesticide with the reported health symptoms among paddy farmers. Methodology: Questionnaires were given to the farmers to obtain the reported health symptoms and 86 blood serum samples were collected. However, only 29 samples were successfully extracted using QuEChERS method (quick, easy, cheap, effective, rugged, and safe) and analysed using the ultra high-performance liquid chromatography-mass spectrometry (UHPLC-MS/MS). Statistical analysis was also used to identify the association of the compounds with the reported health symptoms. Results: The findings showed that the mean of concentrations of azoxystrobin and trifloxystrobin were 165.89 ng mL-1 and 455.86 ng mL-1, respectively. As for the reported health symptoms, there were no significant association for both azoxystrobin and trifloxystrobin. There were other contributing factors such as work duration in years, days and hours, smoking and education level that influenced the reported health symptoms. The reported health symptoms were self-reported by the farmers, which may be inaccurate and may have been the cause of the findings to not be statistically significant. Conclusion: The findings of this study suggest that occupational exposure of pesticides may lead to occurrence of pesticides in blood serum samples of farmers. Since the pesticides are present in blood serum samples of farmers in a significantly higher amount as compared to other studies, further in-depth studies are needed to study the health effects of the pesticides, besides the self-reported respiratory health symptoms. Keywords: pesticides, blood serum sample, ultra-high-performance liquid chromatography- mass spectrometry (UHPLC-MS/MS), QuEChERS method (quick, easy, cheap, effective rugged, and safe)

Item Type:	Project Paper
Faculty:	Faculty of Medicine and Health Science
Depositing User:	Mr Hafizzuddin Hamidon
Date Deposited:	24 Aug 2023 04:56
Last Modified:	24 Aug 2023 04:56
URI:	http://psaspb.upm.edu.my/id/eprint/882

Actions (login required)

View Item