Evaluation of point-of-care glucometers for use in goats

Muzaffar Shah, Nadiah Sakinah (2020) Evaluation of point-of-care glucometers for use in goats. [Project Paper] (Submitted)

Text lp FPV 2020 71.pdf Download (1MB)

Abstract

Glucose concentration is commonly measured in sick animals to assess their health to provide appropriate treatment. Over the years, veterinarians have been using glucometers developed for humans on goats to obtain fast results. However, few studies have been carried out to validate glucometers as a point-of-care tool for goats. In this study, two types of glucometers were evaluated - Accu-check Guide® and Accu-check Active®. Readings from both glucometers were compared to the standard laboratory-based analyser, Biolis 24i clinical chemistry analyser which served as the reference method. The aim of this study was to evaluate the utility of different handheld glucometers in measuring glucose concentration in goats and determine the accuracy between the glucometers and the laboratory-based analyser. A total of 50 healthy adult goats were recruited from 5 farms in Selangor. Blood samples were taken through the jugular venipuncture. A drop of blood was immediately placed onto the test strip for both glucometers while the rest of the blood was stored inside a sodium fluoride and potassium oxalate test tube for analysis with the laboratory-based analyser. One-way ANOVA showed that there was a significant difference in readings from all 3 methods (P<0.05). Accu-check Guide® overestimated (3.24 ± 0.42 mmol/L) while Accu-check Active® underestimated (2.97 ± 0.53 mmol/L) the mean blood glucose concentration when compared to the laboratory-based analyser (3.12 ± 0.39 mmol/L). Using Pearson’s correlation coefficient, Accu-check Guide® (r=0.887) was more highly correlated with laboratory-based analyser than Accu-check Active® (r=0.814). Since the relative bias for both glucometers were within the 5% maximum deviation from reference value, they could be used in goats. In conclusion, Accu-check Guide® is the glucometer of choice as it produced readings that were closer to the laboratory-based analyser with higher correlation and lower relative bias.

Item Type:	Project Paper
Faculty:	Faculty of Veterinary Medicine
Depositing User:	Ms Nurhaznita Mahmood
Date Deposited:	09 Nov 2023 03:26
Last Modified:	09 Nov 2023 03:26
URI:	http://psaspb.upm.edu.my/id/eprint/1519

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